Such variations among individuals' genotypes are inherited - and are the raw material of genetic diversity and evolution. Some of us carry an Alu insertion and some of us do not. Over evolutionary time, up to 1 million copies of the Alu repeat have become randomly inserted throughout the human genome. In this activity, students hunt for a specific Alu repeat (a 300 base pair repetitive sequence of DNA) within a specific region called PV92 on chromosome 16. Extract and amplify genomic DNA from their own samples.Directly measure human diversity at the molecular level.Introduces PCR and applies it to population genetics.Using their own results, students test the Hardy-Weinberg equilibrium theory within their classroom population, then go online to compare their classroom results to genetic data of populations worldwide. With the PV92 PCR Informatics Kit, your students use real-world forensic techniques to extract DNA from their hair follicles or cheek cells, and then use PCR amplification and electrophoresis to fingerprint their own DNA at a specific genetic locus. Run your DNA gels in 10 minutes! Find Out How
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